In patients with Rift Valley Fever brain can suffer a severe inflammation known as Encephalitis. Encephalitis is not very common and arises only in a few cases.
In case of hammoehragic Rift Valley Fever liver damage can also occur in humans. This is associated with the occurrence of some other condition such as jaundice.
In case of Rift Valley Fever lesions are found to arise in animals. However, they are not found to appear in humans.
Rift Valley Fever is caused by the spread of the Rift Valley Fever (RVF) virus which belongs to the Phlebovirus genus, one of the five subtypes of the Bunyaviridae virus. The disease is borne by Rift Valley Fever mosquitoes. When mosquitoes carrying this virus bite livestock, the virus is transmitted to the animals. Rift Valley Fever in animals is caused by the entry of virus from mosquitoes.
Humans failing to wash hands properly after handling the meat, milk, secretions or tissues of these infected animals can contract the disease. Touching the nose with the contaminated hand transmits the virus to the internal system of the body. Humans can also contract the disease directly from mosquito bites. A bite from a mosquito carrying the Phlebovirus virus can also make it enter the body of an individual.
In medical studies regarding Rift Valley Fever climate change is often seen to be a factor. While studying climatic conditions in East Africa, Rift Valley Fever outbreaks were seen to be followed by periods of heavy rainfall. It is not known whether climate change works as a cause behind development of Rift Valley Fever disease.
Rift Valley Fever diagnosis, especially of its acute cases, is done with the help of serological tests like Enzyme-Linked Immunoassay (known as ‘ELISA’ or ‘EIA’). RT-PCR and Antigen Detection tests can also be used for the diagnosis of Rift Valley Fever. These examinations can help detect the presence of Phlebovirus in the early stages of the disease.
The differential diagnosis for Rift Valley Fever involves distinguishing the disease from other similar arboviral and feverous viral conditions.
There is known Rift Valley Fever cure for humans. Several firms are trying to bring out an effective Rift Valley Fever vaccine. However, medical researchers have had some success in using the antiviral drug Ribavirin in monkeys suffering from this condition. Some studies have also found immune modulators and antiviral proteins like interferon quite effective for Rift Valley Fever control.
Rift Valley Fever can be prevented by maintaining proper hygiene. In areas with Rift Valley Fever prevalence, people should wash their hands after handling animal meat, secretions and tissues. This will help avoid Rift Valley Fever transmission and prevent humans from contracting Rift Valley Fever. It will also stop spread of Rift Valley Fever Virus transmission in unaffected animals.
In case of severe Rift Valley Fever, haemorrhages can occur. A haemorrhagic Rift Valley Fever can cause death of a person in 7-10 days. It can result in death of a large number of animals. In the early 1950s, a Rift Valley Fever outbreak resulted in death of over 100,000 sheep.
About 1% of people with Rift Valley Fever are said to die from the condition.
If you are living in an area with high rift valley fever prevalence, it is best to practice good hygiene. This will help you avoid contracting this disease and also prevent others from getting it too. The disease usually goes away in a few days but can give rise to life-threatening complications in a few cases. As there is no specific treatment for this disorder, it is better to guard yourself from this discomforting condition.
References:
http://en.wikipedia.org/wiki/Rift_Valley_fever
http://www.wrongdiagnosis.com/r/rift_valley_fever/intro.htm
http://www.wisegeek.com/what-is-rift-valley-fever.htm
http://www.dhpe.org/infect/rift.html
http://nabc.ksu.edu/content/factsheets/category/Rift%20Valley%20Fever#diagnosis